Disposition of Cocaine in Skin, Interstitial Fluid, Sebum, and Stratum Corneum
نویسندگان
چکیده
منابع مشابه
Skin barrier function and stratum corneum hydration
Under normal circumstances, epidermis must be as impermeable as possible except for a small amount of water loss to hydrate the outer layers of the SC. Although all living cells require water to function, some “dead” cells also require water to be metabolically active. As it is the case of corneocytes, epidermis must retain sufficient water to (a) hydrate the outer layers of the SC to maintain ...
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The skin is the largest organ of the body, whose main function is to protect the body against the loss of physiologically important components as well as harmful environmental insults. From the inside to the outside, the skin comprises three major structural layers: the hypodermis, the dermis and the epidermis. The epidermis contains four different sublayers, the stratum corneum (SC), stratum g...
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The skin is the largest organ of the body, whose main function is to protect the body against the loss of physiologically important components as well as harmful environmental insults. From the inside to the outside, the skin comprises three major structural layers: the hypodermis, the dermis and the epidermis. The epidermis contains four different sublayers, the stratum corneum (SC), stratum g...
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BACKGROUND AND OBJECTIVES Evidence suggests the importance of skin biophysical properties in predicting diseases and in developing appropriate skin care. The results to date of studies on skin surface pH, stratum corneum (SC) hydration and sebum content in both genders and at various ages have been inconclusive, which was in part due to small sample size. Additionally, little is known about the...
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Ever since Ervin Blank discovered1 the importance of moisturizing the stratum corneum, companies have focused their attention on developing a better surface barrier or improving skin surface moisturization in the outer layers of the stratum corneum. More recently, agents such as peroxisomal proliferator-activated receptor (PPAR) ligands have been developed and exploited in moisturizers. These a...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2002
ISSN: 1945-2403,0146-4760
DOI: 10.1093/jat/26.8.547